论文部分内容阅读
目的：探讨性激素受体在转移性肝癌中改变的临床意义；方法：用放射配体结合法测定２１例转移性肝癌和２３例原发性肝癌外周血白细胞雌激素受体（ＥＲ）和白细胞雄激素受体（ＡＲ）；结果：转移性肝癌ＥＲ水平明显低于原发性肝癌ＥＲ（Ｐ＜０．０１）。两组ＡＲ水平无显著差异（Ｐ＞０．０５）。两组ＥＲ置信区域基本不重叠；结论：转移性肝癌可能系非激素依赖性肿瘤，ＥＲ６００位点／细胞可作为区分转移性肝癌和原发性肝癌判断标准之一，其确切价值有待进一步研究
Objective: To investigate the clinical significance of the change of sex hormone receptor in metastatic liver cancer; Methods: To determine the peripheral blood leukocyte estrogen receptor (ER) and leukocyte males in 21 cases of metastatic liver cancer and 23 cases of primary liver cancer by radioligand binding assay Hormone receptor (AR); Results: The ER level of metastatic liver cancer was significantly lower than that of primary liver cancer (P<0.01). There was no significant difference in AR levels between the two groups (P>0.05). The ER confidence regions of the two groups did not substantially overlap; Conclusion: Metastatic liver cancer may be a non-hormone-dependent tumor, ER600 locus/cell may be used as one of the criteria for judging metastatic liver cancer and primary liver cancer, and its exact value needs further study.