许多研究证明，淋巴液的形成是通过淋巴管内皮细胞间的连接和细胞质内的小泡系统两个途径。多数学者认为，淋巴管内皮细胞间连接的开放是中空性器官是淋巴液形成的主要方式，实质性器官以小泡系统为主，并与细菌、异物和用细胞侵入淋巴管密切相关。本文综述了对淋巴管内皮细胞间连接以及胞质内小泡系统的研究情况，探讨了淋巴液形成的形态学基础。 Many studies have shown that the formation of lymph fluid through the lymphatic endothelial cells and cytoplasmic connections within the vesicle system two ways. Most scholars believe that the opening of the lymphatic endothelial cells is the main way for hollow organs to form lymphatic vessels. The main organs are vesicular systems, which are closely related to bacteria, foreign bodies and invasion of lymphatic vessels by cells. This review summarizes the study of lymphatic endothelial cell junctions and the cytoplasmic vesicle system, and discusses the morphological basis of lymphatic fluid formation.