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哮喘是一种气道炎症性疾病,早期使用皮质类固醇吸入剂治疗成人哮喘和儿童哮喘被一致认为是合理有效的。但人们关注长期使用皮质类固醇吸入剂对儿 童的生长发育是否有不良的影响?本研究追踪观察了连续使用布地奈德吸入剂3年以上对哮喘儿童骨密度(BMD)、骨矿量(BMC)、总骨钙(TBC)以及机体组成的影响。 方法根据患儿父母的意愿将哮喘儿童分成布地奈德治疗组(治疗组)和非布地奈德治疗组(对照组)。治疗组157例,对照组111例。每一位患儿均按医生制订的支气管哮喘药物治疗方案和布地奈德吸入量治
Asthma is an airway inflammatory disease, and early use of corticosteroid inhalation for the treatment of adult asthma and childhood asthma was agreed to be valid and effective. However, people are concerned about long-term use of corticosteroid inhalation on children’s growth and development whether there are adverse effects? This study followed the observation of continuous use of budesonide inhalation for 3 years on asthma children’s bone mineral density (BMD), bone mineral content (BMC) , Total bone calcium (TBC) and body composition. Methods Asthmatic children were divided into the budesonide treatment group (treatment group) and the non-budesonide treatment group (control group) according to their parents’ wishes. 157 cases in the treatment group and 111 cases in the control group. Every child was treated according to the doctor’s bronchial asthma medication and budesonide inhalation therapy