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[目的]观察清热解毒散结止痛汤联合西药治疗急性小儿肠系膜淋巴结炎疗效。[方法]使用随机平行对照方法,将85例患者按随机数字表法分为两组。对照组42例中性粒细胞较高,青霉素,100mg/(kg·d),静滴;青霉素过敏,头孢哌酮钠,50mg/(kg·d),静滴;淋巴细胞较高,利巴韦林片,10mg/(kg·d)。治疗组43例清热解毒散结止痛汤(金银花、连翘、黄芩、夏枯草、藿香、半夏、竹茹各6g,昆布、海藻各9g,延胡索醋制、木香、槟榔各6g);1剂/d,水煎两次,取汁100mL;<3岁20mL/次,2次/d;3～6岁40mL/次,2次/d;>6岁50mL/次,2次/d。西药治疗同对照组。连续治疗10d为1疗程。观测临床症状、血常规、腹部B超检查、不良反应。连续治疗1疗程,判定疗效。对85例患者随访1年,观察复发率。[结果]治疗组痊愈14例,显效17例,有效11例,无效1例,总有效率97.68%。对照组痊愈11例,显效15例,有效10例,无效6例,总有效率85.71%。治疗组疗效优于对照组(P<0.05)。复发率治疗组低于对照组(P<0.05)。[结论]清热解毒散结止痛汤联合西药治疗急性小儿肠系膜淋巴结炎疗效显著,值得推广使用。
[Objective] To observe the curative effect of Qingrejiedu Sanjie Zhitong Decoction combined with western medicine on acute children with mesenteric lymphadenitis. [Methods] Using randomized parallel method, 85 patients were divided into two groups according to random number table method. The control group of 42 cases of neutrophils, penicillin, 100mg / (kg · d), intravenous; penicillin allergy, cefoperazone sodium, 50mg / (kg · d), intravenous infusion; higher lymphocytes, ribavirin tablets , 10mg / (kg · d). Treatment group, 43 cases of Qingrejiedu Sanjie Zhitong decoction (honeysuckle, forsythia, skullcap, Prunella vulgaris, Agastache rugosa, Pinellia 6g each, kelp, seaweed each 9g, fumaric vinegar, woody, betel nut each 6g); 1 dose / d, decoction twice, juice 100mL; <3 years old 20mL / times, 2 times / d; 3 to 6 years old 40mL / times, 2 times / d; . Western medicine treatment with the control group. Continuous treatment of 10d for a course of treatment. Observation of clinical symptoms, blood tests, abdominal B-ultrasound, adverse reactions. Continuous treatment of a course of treatment to determine the efficacy. 85 patients were followed up for 1 year, observe the recurrence rate. [Result] The treatment group cured 14 cases, markedly effective in 17 cases, effective in 11 cases, ineffective in 1 case, the total effective rate was 97.68%. The control group recovered in 11 cases, markedly effective in 15 cases, effective in 10 cases, 6 cases, the total effective rate was 85.71%. The treatment group was better than the control group (P <0.05). The relapse rate was lower in the treatment group than in the control group (P <0.05). [Conclusion] Qingrejiedu Sanjie Zhitong Decoction combined with western medicine has significant curative effect on acute pediatric mesenteric lymphadenitis and should be widely used.