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硒是人体必需微量元素之一,硒在维持心脏正常功能和形态上的完整性方面有重要意义。某些动物缺乏硒可引起心肌病变。我国克山病(地方性心肌病)地区的土壤,粮食及居民头发、血和尿液中硒含量明显低于非病区,补充硒可预防克山病发病。血清游离脂肪酸含量与心肌病变发病有关,但硒与血清游离脂肪酸的关系至今未见报导。本实验测定我院克山病研究室饲养的低硒和加硒组仔猪血清中游离脂肪酸的含量,以探讨硒在克山病发病机制中的地位。
Selenium is one of the essential trace elements of the human body. Selenium is important in maintaining the normal function and morphological integrity of the heart. Some animals lack selenium can cause myocardial lesions. The content of selenium in the hair, blood and urine of Keshan disease (endemic cardiomyopathy) areas in our country is obviously lower than that in the non-ward, and the supplement of selenium can prevent the incidence of Keshan disease. Serum free fatty acid levels and the pathogenesis of myocardial disease, but the relationship between selenium and serum free fatty acid has not been reported. In this study, we measured the contents of free fatty acids in sera of piglets fed with low selenium and selenium in our Keshan Disease Research Laboratory to explore the role of selenium in the pathogenesis of keshan disease.