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目的总结儿童药物性胆囊结石(DGST)声像图特点,评价彩色多普勒超声对儿童DGST的诊断价值。方法回顾性分析26例临床诊断为儿童DGST患者资料,根据声像图表现把儿童DGST分为三种类型:团块型、泥沙型和悬浮型。把团块型DGST与随机选取经手术治疗的60例成人胆囊结石资料(GST)对比分析。结果 26例DGST患者中团块型14例,泥沙型8例,悬浮型4例。团块型DGST声像图表现为结石形态不规则、结构松散,与成人GST比较差异有统计学意义(P<0.05),儿童DGST结石直径与用药时间呈正相关(r=0.946,P<0.001),与停药后消失时间无相关性(r=0.226,P=0.267)。结论儿童DGST声像图表现和临床转归与成人GST不同,超声检查结合用药史和停药后结石消失的特点可做出提示性诊断。
Objective To summarize the characteristics of pediatric DGG and evaluate the diagnostic value of color Doppler ultrasound in children with DGST. Methods A retrospective analysis of 26 cases of clinically diagnosed children with DGST data, according to sonographic DGPS children into three types: clumps, sediment and suspension. Sixty patients with gallstone masses (GST) were randomly divided into two groups. Results Of the 26 patients with DGST, 14 were clump type, 8 were sediment type and 4 were suspension type. There was a significant difference between the two groups (P <0.05). The diameter of DGST stones was positively correlated with the time of treatment (r = 0.946, P <0.001) , There was no correlation with the disappearance time after stopping (r = 0.226, P = 0.267). Conclusion The presentation and clinical outcome of DGST in children are different from those of adult GST. Ultrasound examination combined with the history of medication and the disappearance of stones after stopping can make suggestive diagnosis.