目的研究胃、肝、肠组织细胞上的幽门螺旋杆菌（ＨＰ）受体样物质。方法采用酶免疫亲和配体法及用大肠杆菌，空肠弯曲菌作特异性阻断试验。结果ＨＰ受体样物质仅存在于胃粘膜细胞，不能被大肠杆菌，空肠弯曲菌阻断。同时发现采用高碘酸氧化法检测表明此物质与粘多糖蛋白有关，在体外试验中能够增强ＨＰ的抗吞噬能力。结论ＨＰ受体样物质具有组织和细菌种属特异性 Objective To study Helicobacter pylori (HP) receptor-like substances on gastric, hepatic and intestinal tissue cells. Methods Enzyme immunoaffinity ligand method and Escherichia coli, Campylobacter jejuni specific blocking test. Results HP receptor-like substance only exists in gastric mucosal cells, can not be E. coli, Campylobacter jejuni blocked. Also found that the use of periodate oxidation test showed that the substance and mucopolysaccharide-related, in vitro tests can enhance the HP anti-phagocytic ability. Conclusion HP receptor-like substances have tissue and bacterial species specificity