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为探讨几种药物对气管插管时心血管副反应的预防作用，将１０２例择期手术病人随机分为对照组、氟芬组、三磷酸腺苷组、硫酸镁组、芬太尼组和利多卡因组共六组．分别比较诱导前，插管时和插管后５ｍｉｎ的ＭＡＰ，ＨＲ，ＳＢＰ和ＲＰＰ，结果发现：芬太尼，氟芬合剂能有效地预防心血管副反应，是两种理想的药物．三磷酸腺苷能防止插管时的血压升高，但不能预防心率增快和心肌耗氧量的增加．利多卡因虽有一定作用但效果不理想．而５０ｍｇ／ｋｇ的硫酸镁不能有效地预防心血管副反应的发生．
To investigate the preventive effect of several drugs on cardiovascular adverse reactions during tracheal intubation, 102 patients undergoing elective surgery were randomly divided into control group, flutamide group, adenosine triphosphate group, magnesium sulfate group, fentanyl group and lidocaine group A total of six groups. The results of MAP, HR, SBP and RPP before induction, intubation and 5 min after intubation were compared. It was found that fentanyl and flurbin combined agents can effectively prevent cardiovascular side effects and are two ideal drugs. Adenosine triphosphate can prevent high blood pressure during intubation, but can not prevent heart rate and myocardial oxygen consumption increased. Although lidocaine has a certain effect, its effect is not satisfactory. However, 50mg / kg of magnesium sulfate can not effectively prevent the occurrence of cardiovascular side effects.