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[目的]了解不同人群甲型H1N1流感(甲流)抗体水平与甲流疫苗接种后的免疫效果,为预测甲流提供参考依据。[方法]2010年1月,采集南阳市卧龙区部分普通人群、甲流确诊病例和甲流疫苗接种者血清,采用血凝抑制试验检测甲流抗体水平。[结果]检测普通人群138人,甲流抗体阳性的26人,阳性率为18.84%,几何平均滴度为1∶17.73,其中>60岁、20~61岁、3~5岁、6~18岁阳性率分别为为47.22%、11.43%、8.57%、6.25%(P<0.01)。检测甲流确诊病例25例,甲流抗体阳性的22例,阳性率为88.00%,几何平均滴度为1∶40.00。检测甲流疫苗接种者126人,甲流抗体阳性的105人,阳性率为83.33%,几何平均低度为1:41.12。[结论]卧龙区普通人群甲流抗体水平较低,甲流病人和甲流疫苗接种者甲流抗体水平较高。
[Objective] To understand the antibody level of Influenza A (H1N1) in different populations and the immune effect after Influenza A vaccination, and provide a reference for predicting the flow of Influenza A (H1N1). [Method] In January 2010, the serums of some ordinary people, the confirmed cases of A and the A flu vaccine were collected from Wolong District in Nanyang City, and the level of antibody to A streptococci was detected by using the hemagglutination inhibition test. [Results] The positive rate was 18.84%, the average geometric mean titer was 1:17.73, of which 138 were in the general population, 26 were in the range of 20 to 61 years old, 3 to 5 years old, 6 to 18 The positive rates were 47.22%, 11.43%, 8.57% and 6.25% respectively (P <0.01). 25 cases were diagnosed as ameloblastoma, 22 cases were positive for influenza A antibody, the positive rate was 88.00%. The geometric mean titer was 1:40.00. A total of 126 influenza virus A vaccinees were detected, and 105 were positive for influenza A antibody. The positive rate was 83.33%. The average geometric mean was 1: 41.12. [Conclusion] The prevalence of influenza A antibody in the general population is relatively low in Wolong district, and the level of antibody to influenza A in patients with H1N1 influenza A and H1N1 vaccines is higher.