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七十年代以来随着快速强利尿剂及血管扩张剂等应用于充血性心力衰竭(简称心衰),疗效有明显的提高。现仅就目前治疗的进展,简述如下:从生理及病理生理研究,发现心脏排出量的改变,主要取决于四个因素,即心肌收缩力、前负荷、后负荷及心率的变化。当发生心衰时,首先产生血液动力学的异常改变,表现为心排出量降低及左室舒张末期压力增高,而症状出现则较迟,故对心衰患者,应主要针对上述四个因素进行治疗。过去用强心利尿等各种治疗均无良好反应,所谓难治性(顽固性)心衰概念,也在随着治疗条件的改善而
Since the seventies with rapid diuretics and vasodilators and other applications in congestive heart failure (referred to as heart failure), the effect was significantly improved. Now just the progress of the current treatment, summarized as follows: From physiological and pathophysiological studies found that changes in cardiac output, mainly depends on four factors, namely, myocardial contractility, preload, afterload and heart rate changes. When heart failure occurs, first of all have abnormal hemodynamic changes, manifested as decreased cardiac output and left ventricular end-diastolic pressure increased, while the symptoms appear later, so heart failure patients, mainly for the above four factors treatment. In the past with cardiac diuretic and other treatments are not good response, the so-called refractory (refractory) concept of heart failure, but also with the improvement of treatment and