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原癌基因HER2/neu编码分子量为185kDa的跨膜酪氨酸激酶生长因子,在许多类型肿瘤中都过度表达,HER2/neu在肿瘤组织中的高水平使它成为一种具有潜在应用前景的研制治疗性抗体的肿瘤相关抗原。细胞因子在诱导和控制机体免疫应答中起重要作用,美国加州大学Helguera等研究了白细胞介
The proto-oncogene HER2 / neu encodes a transmembrane tyrosine kinase growth factor of 185 kDa, overexpressed in many types of tumors and the high level of HER2 / neu in tumor tissues makes it a potentially viable development Tumor-associated antigens for therapeutic antibodies. Cytokines play an important role in inducing and controlling the immune response in the body. Helguera et al.