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目的探讨NCPAP在婴儿重症肺炎合并呼吸衰竭中的疗效。方法选取我院ICU的婴儿重症肺炎合并呼吸衰竭患儿37例,随机分为对照组、治疗组。两组均予常规治疗,对照组面罩吸氧,治疗组应用NCPAP治疗。分析以下各参数呼吸频率、心率、动脉血氧分压及氧合指数在治疗前、治疗24h后的变化。结果治疗组与对照组患儿治疗前RR、HR、PaO2及PaO2/FiO2比较,差异无统计学意义,而治疗24h后各指标比较,差异均有统计学意义(P<0.05)。结论对婴儿重症肺炎合并呼吸衰竭者,宜早期使用NCPAP,可改善患儿的临床症状、降低气管插管机会,无明显副作用。NCPAP治疗中如呼吸困难无改善,尽早给予机械通气。
Objective To investigate the efficacy of NCPAP in severe pneumonia complicated with respiratory failure in infants. Methods Thirty-seven infants with severe pneumonia and respiratory failure in ICU of our hospital were randomly divided into control group and treatment group. Both groups were given routine treatment, the control group mask oxygen, the treatment group treated with NCPAP. Analysis of the following parameters respiratory rate, heart rate, arterial oxygen tension and oxygenation index before treatment, 24h after treatment changes. Results There was no significant difference in RR, HR, PaO2 and PaO2 / FiO2 between treatment group and control group before treatment, but there was significant difference between each index after treatment for 24 hours (P <0.05). Conclusion Severe pneumonia in infants with respiratory failure should be early use of NCPAP, can improve the clinical symptoms of children, reduce the chance of tracheal intubation, no obvious side effects. NCPAP treatment, such as no improvement in breathing difficulties, give mechanical ventilation as soon as possible.