创新药开发1.正确定位据国外权威机构统计,开发成功一种新药的费用中75%以上消耗在前期研究的失败和挫折中。在化合物被作为候选药物进入临床前开发之后,仍有99%的淘汰率。美国Lehmann Brothers估计,2005年研究一种新药并成功上市,其开发成本飚升至16亿美元(20世纪末为5亿美元左右),并有进一步增长的发展。国内新药开发成本可能要低得多,但设想一下药品研究开发的漫长过程和如此高的淘汰率,企业应该有清醒认识。 Innovative drug development 1. Proper positioning According to foreign authorities statistics, the successful development of a new drug cost more than 75% of the consumption in the failure and setbacks in previous studies. There is still a 99% elimination rate after the compound is introduced as a candidate drug into the preclinical development. Lehmann Brothers estimates that in 2005 a new drug was researched and marketed. Its development cost soared to 1.6 billion U.S. dollars (about 500 million U.S. dollars in the late 20th century) and further growth was expected. Domestic new drug development costs may be much lower, but imagine the long process of drug research and development and such a high rate of elimination, companies should have a clear understanding.