间尼索地平是一个新型的二氢吡啶类钙通道拮抗药,可望成为防治冠心病、心绞痛、高血压病的理想新药。本文综述近年来对间尼索地平在心血管方面的研究成果,为其进一步的临床研究打下基础。1间尼索地平的降压作用1.1间尼索地平能降低正常血压、麻醉犬、麻醉家兔、清醒家兔及清醒 Inter-nisoldipine is a novel dihydropyridine calcium channel antagonist, which is expected to be an ideal new drug for the prevention and treatment of coronary heart disease, angina and hypertension. This review summarizes the recent advances in cardiovascular research of meta-nisoldipine, laying the foundation for further clinical research. 1 nisoldipine antihypertensive effect 1.1 nisoldipine can reduce the normal blood pressure, anesthetized dogs, anesthetized rabbits, awake rabbits and awake