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为探讨凝血象在膀胱肿瘤患者中的改变，分别采用全自动血细胞分析法、血凝法和定量酶联免疫吸附法对膀胱肿瘤组凝血象指标，包括血小板（PLT）、血小板平均体积（MPV）、血小板比积（PCT）和血小板平均宽度（PDW）以及凝血酶原时间（PT）、部分凝血活酶时间（APTT）、纤维蛋白原（Fbg）和D－二聚体予以测定，并与非肿瘤组进行比较。结果膀胱肿瘤组PLT较非肿瘤组明显增高（P＜0.01），MPV降低（P＜0.05），PCT较非肿瘤组有极显著性差异（P＜0.01）；而PDW、PT、APTT及Fbg无显著性差异（P＞0．05）；膀胱肿瘤组D－二聚体含量明显高于非肿瘤组（P＜0．01）。认为膀胱肿瘤患者凝血象指标异常，其中以PLT、PCT和D－二聚体改变尤为明显。
To investigate the changes of blood coagulation in patients with bladder tumors, blood coagulation parameters, including platelet (PLT) and mean platelet volume (MPV), were measured using the automated hematology analysis, hemagglutination, and quantitative enzyme-linked immunosorbent assays, respectively. , platelet ratio (PCT) and mean platelet width (PDW) and prothrombin time (PT), partial thromboplastin time (APTT), fibrinogen (Fbg), and D-dimer were measured, and The tumor group was compared. Results PLT in bladder cancer group was significantly higher than that in non-tumor group (P<0.01), MPV was decreased (P<0.05), PCT was significantly different from non-tumor group (P<0.01), but PDW, PT, APTT, and Fbg were not. Significant difference (P>0.05); D-dimer content in bladder tumor group was significantly higher than non-tumor group (P <0.01). It is considered that the coagulation parameters of bladder cancer patients are abnormal, especially PLT, PCT and D-dimer changes.