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目的探讨新生儿呼吸衰竭高频振荡通气治疗的临床疗效。方法 60例新生儿呼吸衰竭患儿随机分为观察组和对照组,每组30例,对照组采用常规机械通气治疗,观察组采用高频振荡通气治疗,比较两组患者的临床疗效。结果两组患儿治疗前吸入氧浓度、氧合指数、动脉血二氧化碳分压(Pa CO2)、Pa O2/Pa CO2比较差异无统计学意义(P>0.05),治疗后48 h两组患儿上述各指标均所有改善,且观察组患者改善程度明显优于对照组,差异有统计学意义(P<0.05);采用不同方式治疗后观察组患者的并发症发生率明显低于对照组,差异有统计学意义(P<0.05)。结论针对新生儿呼吸衰竭患儿实施高频振荡通气治疗可显著改善患儿肺通气氧合功能,并可减少并发症发生,临床价值显著,可推广应用。
Objective To investigate the clinical efficacy of high-frequency oscillatory ventilation in neonatal respiratory failure. Methods Sixty neonates with respiratory failure were randomly divided into observation group (n = 30) and control group (n = 30). The control group was treated by conventional mechanical ventilation. The observation group was treated by high frequency oscillatory ventilation. The clinical efficacy was compared between the two groups. Results Before treatment, there was no significant difference in oxygen uptake, oxygenation index, arterial carbon dioxide partial pressure (Pa CO2) and Pa O2 / Pa CO2 between the two groups (P> 0.05) The above indicators all improved, and the observation group patients improved significantly better than the control group, the difference was statistically significant (P <0.05); after treatment with different ways the observation group patients with complication rate was significantly lower than the control group, the difference There was statistical significance (P <0.05). Conclusion The treatment of neonatal respiratory failure with high-frequency oscillatory ventilation can significantly improve the pulmonary ventilation and oxygenation in children and reduce the incidence of complications, the clinical value is significant and can be extended to use.