Sarcophytol-A,2—异丙基—5,9,13—三甲基—2(Z),4(E),8(E),12(E)—十四碳环四烯—1—醇(1),是Mitsuhashi等人1979年从日本南部海域的软珊瑚中分离鉴定的大环二萜类化合物之一。药理实验表明其具有抗肿瘤活性。到目前为止,这类化合物的全合成研究报道很少。前文我们已报道了Sarcophytol-A前体化合物 Sarcophytol-A, 2-isopropyl-5,9,13-trimethyl-2 (Z), 4 (E), 8 (E) (1) is one of the macrocyclic diterpene compounds isolated and identified by Mitsuhashi et al. In 1979 from soft corals in the southern waters of Japan. Pharmacological experiments show that it has anti-tumor activity. Until now, there have been few reports on total synthesis of these compounds. We have previously reported Sarcophytol-A precursor compounds