论文部分内容阅读
过氧化物酶增殖剂激活受体(Peroxisome Pro-liferator-Activated Receptor,PPARγ)是调节目标基因表达的核内受体转录因子超家族成员[1]。有文献报道由于PPARγ在脂肪,肾和胚胎发育过程的基本作用,PPARγ敲除的小鼠是胚胎致死性的。在发现PPARγ在巨噬细胞也有表达后,人们提出P
Peroxisome proliferator-activated receptor (PPARγ) is a member of the nuclear receptor transcription factor superfamily regulating target gene expression [1]. It has been reported that PPARγ knockout mice are embryonic lethal due to the basic role of PPARγ in fat, kidney and embryonic development. After it was found that PPARγ was also expressed in macrophages, it was suggested that P