为探讨毒瘾患者感染性心内膜炎的临床特征，本文对毒瘾组（８例）和非毒瘾组（２１例）感染性心内膜炎的临床表现和超声特征进行了对比分析。结果显示，毒瘾组金黄色葡萄球菌为主要致病菌，其阳性检出率（６２５％）较非毒瘾组（１９％）明显增高（Ｐ＜００１）；毒瘾组发热体温３９７±０４°Ｃ，较非毒瘾组３８５±０７°Ｃ高（Ｐ＜００５），且多伴寒颤、肌肉酸痛；肺栓塞发生率毒瘾组（６２５％，５／８）高于非毒瘾组（４７％，１／２１）（Ｐ＜００１），而外周栓塞发生率毒瘾组（１２５％，１／８）低于非毒瘾组（４２９％，９／２１）（Ｐ＜００１）；超声发现毒瘾组心腔赘生物检出６例（７５０％），均位于右侧心腔，而非毒瘾组检出１５例（７１４％），主要位于左侧心腔，毒瘾组赘生物较大，最大长度２２±０８（１２～３４）ｃｍ，非毒瘾组只有０９±０３（０５～１５）ｃｍ（Ｐ＜００１）。 To explore the clinical features of infective endocarditis in drug addicts, the clinical features and sonographic features of infective endocarditis in drug addicts (n = 8) and non-addicts (n = 21) were compared. The results showed that Staphylococcus aureus was the main causative agent in the drug addiction group, the positive rate was 62.5% compared with 19% in non-drug addicts group (P <001) Body temperature 39  7  0  4 ° C, 38  5  0  7 ° C higher than non-drug addiction group (P <0  05), and more with chills, muscle soreness; incidence of pulmonary embolism drug addiction group 62.5%, 5/8) were higher than those in non-drug addiction group (4.7%, 1/21) (P <0.01), while the rate of peripheral embolism was 12.5% ​​(1/8) ) Were lower than those in non-drug addiction group (429%, 9/21) (P <001). Six cases (750%) were found in the addicted group 15 cases (714%) were detected in the cavity, but not in the drug addiction group, which were mainly located in the left heart cavity. The neoplastic area in the addiction group was larger with a maximum length of 22 ± 08 (12 ~ 34 ) Cm, only 09 ± 03 (05 ~ 15) cm in non-drug addiction group (P <001).