目的：寻找减少甲亢术后复发和甲减发生的方法。方法：甲亢病例中１１例（Ⅰ组）行核素显像后按局部功能高低切除腺体，８８例（Ⅱ组）按目前普遍采用的次全切除术切除腺体，所有病例术后随访９个月～１８个月，平均１２个月。结果：Ⅰ组无术后甲亢复发，发生甲减１例（０９１％）；Ⅱ组甲亢复发５例（５６８％），甲减发生７例（７９５％），２组病例甲亢复发及甲减发生存在显著性差异（均Ｐ＜００５）。结论：核素显像指导甲亢手术具有重要的临床实用价值 Objective: To find ways to reduce recurrence and hypothyroidism after hyperthyroidism. Methods: Eleven cases of hyperthyroidism (group Ⅰ) underwent radionuclide excision according to local function after radiography, and 88 cases (group Ⅱ) underwent gonadectomy using the commonly used subtotal resection. All patients were followed up for 9 years Months to 18 months, an average of 12 months. Results: In group Ⅰ, there was no recurrence of hyperthyroidism, hypothyroidism occurred in 1 case (091%); in group Ⅱ, 5 cases (568%) were hyperthyroidism recurrence, 7 cases (795%) in hypothyroidism, 2 cases Hyperthyroidism recurrence and hypothyroidism were significantly different (P <0  05). Conclusion: Radionuclide imaging has important clinical value in guiding hyperthyroidism