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目的探讨延吉市居民血尿酸、血脂与血压水平的关系。方法 2007年在延吉市社区人群中进行健康体检,对除外肝、肾、心脑血管疾病以及糖尿病等内分泌疾病者随机抽取1154名测定血压和血尿酸(UA)、甘油三脂(TG)、总胆固醇(TC)、低密度脂蛋白胆固醇(LDL-C)和高密度脂蛋白胆固醇(HDL-C),并比较高血压组和正常血压组的血脂和UA水平。结果调整年龄和体质指数(BMI)后,高血压组中男性UA和TC,女性UA、TC和TG水平均高于正常血压组(P<0.05);高血压组高TC、高TG、高LDL-C和高UA率高于正常血压组(P<0.05);校正年龄、性别和BMI后,UA与TC、TG均呈正相关(r值分别为0.109,0.176,P<0.05)。结论血UA、血脂水平与高血压有一定的相关性,有必要将UA测定作为高血压常规检查项目。
Objective To investigate the relationship between blood uric acid, blood lipids and blood pressure in Yanji residents. Methods A total of 1154 patients with endocrine diseases except liver, kidney, cardio-cerebrovascular disease and diabetes mellitus were enrolled in this study. The blood pressure, blood uric acid (UA), triglyceride (TG) Cholesterol (TC), low density lipoprotein cholesterol (LDL-C) and high density lipoprotein cholesterol (HDL-C) were measured. Blood lipids and UA levels were compared between hypertensive group and normotensive group. Results After adjustment for age and body mass index (BMI), the levels of UA and TC, UA, TC and TG in male were higher than those in normal group (P <0.05). The levels of high TC, high TG and high LDL (P <0.05). After adjusting for age, gender and BMI, UA was positively correlated with TC and TG (r = 0.109 and 0.766, P <0.05, respectively). Conclusion Blood UA, blood lipid levels and hypertension have some relevance, it is necessary to UA determination as a routine examination of hypertension.