论文部分内容阅读
对于钙与铅间的代谢关系认识已久。在50年前就提出用含钙饮食来有效地预防,甚至治疗职业性铅中毒。到1950年,临床上开始应用铅的螯合剂如依地酸钙。最近认识到低钙饮食可大大增强对铅的易感性和病理作用。进食低钙饲料(0.1%)和饮用含铅12ppm水的大鼠,其软组织中铅的蓄积与进食正常含钙饲料(0.7%)和饮用含铅200ppm水的相似。已证实,低钙饮食可增加大鼠对铅的滞留及其他种动物对铅毒的易感性。这种观察可能对于目前城市儿童特别重要,现已知城市儿童血铅高于40μg/100ml,并可能有铅
Metabolic relationship between calcium and lead for a long time. 50 years ago proposed the use of calcium diet to effectively prevent, and even the treatment of occupational lead poisoning. By 1950, the clinical application of lead chelators such as calcium edetate. Recently, it has been recognized that a low-calcium diet can greatly enhance the susceptibility to lead and pathological effects. Rats fed low-calcium diets (0.1%) and drank lead-containing 12 ppm water had similar accumulation of lead in their soft tissues as normal calcium-containing feeds (0.7%) and drinking lead-containing 200 ppm water. Has confirmed that low-calcium diet can increase rat retention of lead and other species of lead susceptibility to lead poisoning. This observation may be of particular importance to current urban children, and it is now known that urban children have elevated blood lead levels above 40 μg / 100 ml and may have lead