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目的分析都江堰市人民医院药品不良反应(ADR)的发生情况及引发ADR的相关因素,为临床合理用药及正确评价ADR的发生提供参考。方法对医院2009年1月-2011年12月收集上报至全国ADR监测网络的168例ADR报告,进行回顾性分类与统计分析。结果 ADR报告例数最多的为临床科室,男女病例数比为0.87∶1,静脉给药途径引发的ADR最多(占77.98%);抗感染药物的ADR发生率最高(占61.90%);皮肤及其附件损害最常见占(27.98%)。结论抗感染药物和中药注射剂是ADR监测的重点药物,应加强ADR监测及相关知识的宣传,提高合理用药水平,减少药源性疾病的发生。
Objective To analyze the incidence of adverse drug reaction (ADR) and the related factors of ADR in Dujiangyan People’s Hospital, and provide reference for clinical rational use of drug and correct evaluation of ADR. Methods 168 cases of ADR reported to the national ADR monitoring network from January 2009 to December 2011 were collected and retrospectively classified and statistically analyzed. Results The most cases of ADR were clinical departments, the ratio of male to female was 0.87:1, the most ADR was caused by intravenous route (77.98%), the highest rate of ADR was anti-infective (61.90%), The most common attachment damage (27.98%). Conclusion Anti-infective drugs and Chinese medicine injection are the key drugs for ADR monitoring. We should strengthen the publicity of ADR monitoring and related knowledge to improve the rational use of drugs and reduce the occurrence of drug-induced diseases.