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造血干细胞移植是治愈慢性粒细胞白血病(CML)的唯一方法,本文报告了无关供髓移植治疗CML的结果。 病人196例,临床表现、细胞形态、细胞遗传学(Ph染色体全部阳性)均符合CML,且在慢性期。男100例,女96例,中位年龄35(1～55)岁,从诊断到移植的中位时间1.4(1～14.6)年;无关供髓者男112例,女84例,其中无妊娠史26例,≥1次妊娠56例,不详2例,中位年龄38(19～58)岁。骨髓配型:HLA-
Hematopoietic stem cell transplantation is the only way to cure chronic myelogenous leukemia (CML). This article reports the results of unrelated myeloid transplantation for the treatment of CML. Of the 196 patients, clinical manifestations, cell morphology, and cytogenetics (all Ph chromosomes were positive) were consistent with CML and were in the chronic phase. There were 100 males and 96 females, with a median age of 35 (1 to 55) years. The median time from diagnosis to transplantation was 1.4 (1 to 14.6) years. There were 112 males and 84 females who were unrelated to the donor. There were no pregnancies. History of 26 cases, ≥ 1 pregnancy in 56 cases, 2 cases were unknown, the median age of 38 (19 to 58) years old. Bone Marrow Matching: HLA-