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目的 观察０ ．３／ ｍｌ 的丝裂霉素Ｃ（ Ｍ ＭＣ） 作用时间３ ｍｉｎ 对青光眼小梁切除术疗效的影响及其并发症的防治。方法 选择３０ 例４３ 眼青光眼在小梁切除术中应用Ｍ ＭＣ，３０ 例４５ 眼青光眼单纯行小梁切除术作为对照组，术前两组患者资料统计学处理无差异。观察两组术前：术后眼压、滤过泡、前房、并发症等，并将结果作统计学处理。随访时间６ ～２４ 月，平均１２ ±２ ．６ 月。结果 两组术后眼压均较术前显著降低，术后前房恢复时间无差异。Ｍ ＭＣ 组多表现为苍白隆起壁较薄滤泡，对照组多为弥漫扁平充血滤泡， ＭＭＣ 组术后成功率为９７ ．６ ％ ，对照组成功率８４ ．４４ ％ ，有统计学差异。术后并发症Ｍ ＭＣ组主要是低眼压，但未发现有持续性低眼压性黄斑病变者，其余并发症有结膜创口漏、脉胳膜脱离及白内障加重，两组无差异。结论 ０ ．３ ｍ ｇ／ ｍｌＭＭＣ 作用时间３ ｍｉｎ 可提高抗青光眼小梁切除术的成功率，强调严格选择适应症，术中彻底清除残余ＭＭＣ，预防低眼压等并发症。
Purpose To observe 0. 3 / ml mitomycin C (M MC) action time of 3 min on the efficacy of trabeculectomy and its prevention and treatment of glaucoma. Methods Thirty patients (43 eyes) with glaucoma were treated with MCM in trabeculectomy and 30 cases with 45 eyes of glaucoma alone. The data of two groups before operation were not statistically different. Preoperative two groups were observed: intraocular pressure, filtration bleb, anterior chamber, complications, and the results for statistical analysis. Follow-up time 6 to 24 months, an average of 12 ± 2. June. Results The postoperative IOP of both groups was significantly lower than that before operation, and there was no difference in the recovery time of anterior chamber after operation. M MC group showed more pale bulge wall follicles, the control group mostly diffuse flat congestion of the follicles, MMC group after the success rate of 97. 6%, control group success rate of 84. 44%, there is a statistical difference. Postoperative complications M MC group is mainly low intraocular pressure, but no persistent low intraocular pressure macular degeneration found, the remaining complications were conjunctival wound leakage, the incidence of extracapsular venous distention and cataracts, no difference between the two groups. Conclusion 0. 3 m g / mlMCMC role of 3 min can improve the success rate of anti-glaucoma resection, emphasizing the strict selection of indications, intraoperative removal of residual MMC, prevention of complications such as hypotony.