Aim: To find out the changes induced by lindane on the antioxidant enzymes in epididymis and epididymal sperm ofadult rats. Methods: Adult male rats were orally administered lindane at a dose of 5.0 mg/kg body weight per dayfor 30 days. At the end of the treatment, the rats were sacrificed. The epididymis was removed and weighed and spermwere collected for sperm count, motility and biochemical studies. A 1% homogenate of epididymis was prepared andused for biochemical estimations. Results; In lindane-treated rats, there were significant reductions in the epididy-mal weight, epididymal sperm count and motility compared with the controls. Significant decreases in the superoxidedismutase (SOD), catalase, glutathione reductase and glutathione peroxidase activities and significant increases in theH_2O_2 generation and lipid peroxidation were also observed in the epididymis and epididymal sperm of lindane-treatedrats. Conclusion; Lindane decreases the levels of antioxidant enzymes in the epididymis and epidid Aim: To find out the changes induced by lindane on the antioxidant enzymes in epididymis and epididymal sperm of adult rats. Methods: Adult male rats were orally administered lindane at a dose of 5.0 mg / kg body weight per day for 30 days. At the end of the treatment, the rats were sacrificed. The epididymis was removed and weighed and spermwere collected for sperm count, motility and biochemical studies. A 1% homogenate of epididymis was prepared and used for biochemical estimations. Results; In lindane-treated rats, there were significant reductions in the epididy-mal weight, epididymal sperm count and motility compared with the controls. Significant decreases in the superoxidedismutase (SOD), catalase, glutathione reductase and glutathione peroxidase activities and significant increases in the H2O2 generation and lipid peroxidation were also observed in the epididymis and epididymal sperm of lindane-treated rats. Conclusion; Lindane decreases the levels of antioxidant enzymes in the epi didymis and epidid