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目的:探讨血清尿酸水平与冠心病发生、发展的相关性。方法:选取187例行冠状动脉造影患者,根据冠状动脉造影结果分为冠心病组和对照组,对2组患者血清尿酸水平及冠状动脉造影结果进行分析。结果:冠心病组血清尿酸水平高于对照组(P<0.05),其中多支病变组最高;以冠心病为因变量,年龄、性别、血脂、尿酸等为自变量进行二分类Logistic回归分析结果显示,年龄、糖尿病史、血清尿酸水平是冠心病危险因素。结论:血清尿酸与冠心病的发生、发展及病变程度相关,可能是冠心病的独立危险因素。
Objective: To investigate the correlation between serum uric acid level and occurrence and development of coronary heart disease. Methods: 187 patients undergoing coronary angiography were selected and divided into coronary heart disease group and control group according to the results of coronary angiography. Serum uric acid level and coronary angiography results were analyzed in two groups. Results: The level of serum uric acid in coronary heart disease group was higher than that in control group (P <0.05), and the highest was in multi-vessel disease group. Logistic regression analysis was performed using coronary heart disease as dependent variable, age, gender, serum lipids and uric acid as independent variables Show, age, history of diabetes, serum uric acid levels are risk factors for coronary heart disease. Conclusion: Serum uric acid is associated with the occurrence, development and severity of coronary heart disease, which may be an independent risk factor for coronary heart disease.