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目的探讨社区获得性肺炎药物敏感性、病原耐药等情况,为临床诊断、治疗提供有效依据,同时观察其临床疗效及安全性。方法对我科收治的社区获得性肺炎患者84例随机分成两组:治疗组(阿奇霉素组)和对照组(左氧氟沙星组),每组各42例,治疗组以阿奇霉素序贯疗法,对照组以左氧氟沙星序贯疗法进行临床比较观察。结果阿奇霉素序贯治疗组疗程短,优于对照组,比较差异有统计学意义(P<0.05)。结论阿奇霉素序贯治疗社区获得性肺炎疗效更为确切,可作为社区获得性肺炎的一线用药。
Objective To investigate the drug sensitivity and pathogen resistance of community-acquired pneumonia and to provide an effective basis for clinical diagnosis and treatment, and to observe its clinical efficacy and safety. Methods Eighty-four patients with community-acquired pneumonia admitted to our department were randomly divided into two groups: treatment group (azithromycin group) and control group (levofloxacin group), 42 cases in each group. The treatment group was treated with azithromycin sequential therapy, while the control group was treated with levofloxacin Sequential therapy for clinical comparative observation. Results Azithromycin sequential treatment group shorter course, better than the control group, the difference was statistically significant (P <0.05). Conclusion Sequential azithromycin treatment of community-acquired pneumonia is more accurate and can be used as first-line treatment for community-acquired pneumonia.