放射性脑水肿是指放射线(包括γ-射线、X线)照射所诱发的脑水肿,其潜伏期长短不一,最短者放疗后即出现,长可达数年之久,但多发生于放疗后数月～1或2年内,与放射剂量有直接的关系,剂量越大,发生率越高,且持续时间长,消散困难。β-七叶皂甙钠(β-Aescine Sodium)的临床应用屡见报道,但尚未有应用于放射性脑水肿的研究报道,本文对比观察β-七叶皂甙钠、甘露醇、地塞米松治疗28例放射性脑水肿的疗效,并对其作用机理及优缺点进行讨论。 Radiation brain edema refers to the brain edema induced by radiation (including gamma-ray and X-ray) irradiation. Its incubation period is of different lengths. The shortest ones appear after radiotherapy and may last for several years, but most often occur after radiotherapy. Within 1 month or 2 years, there is a direct relationship with the radiation dose. The higher the dose is, the higher the incidence is, and the longer it lasts. It is difficult to dissipate. The clinical application of β-Aescine Sodium has been reported frequently, but there is no report on the application of radioactive brain edema. This study compared 28 patients with β-aescin sodium, mannitol and dexamethasone. The efficacy of radiation brain edema, and its mechanism of action and the advantages and disadvantages discussed.