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目的:探讨手术治疗颅脑外伤继发顽固性癫痫的临床效果。方法:选取2009年8月-2011年7月在大连医科大学附属第二医院接受手术治疗的颅脑外伤继发顽固性癫痫患者42例为观察对象,所有患者均接受手术治疗,回顾分析患者的临床治疗效果。结果:42例观察对象中,III级6例,II级8例,I级28例。全部患者均出现颞叶、额叶软化现象。患者前颞叶病理变化主要表现为颞叶皮质结构异常并发海马硬化、单纯性颞叶皮质细胞结构异常以及外伤性颞叶皮质分层结构异常等。结论:本次研究证实,手术治疗是一种较为有效的临床治疗颅脑外伤继发顽固性癫痫的方法,应根据患者临床表现和诱发原因的不同,选择是否手术治疗。
Objective: To investigate the clinical effect of surgical treatment of intractable epilepsy secondary to craniocerebral trauma. Methods: From August 2009 to July 2011, 42 patients with intractable epilepsy secondary to surgery for traumatic brain injury in the Second Affiliated Hospital of Dalian Medical University were selected as the observation subjects. All the patients underwent surgical treatment. The patients’ Clinical treatment effect. Results: Of the 42 subjects, 6 were in grade III, 8 in grade II and 28 in grade I. All patients showed temporal lobe, frontal softening phenomenon. Pathological changes in the anterior temporal lobe of patients with temporal lobe cortical structure abnormalities complicated by hippocampal sclerosis, simple temporal lobe cortical cell structure abnormalities and traumatic temporal cortical stratification structure abnormalities. Conclusion: This study confirmed that surgical treatment is a more effective clinical treatment of intractable epilepsy secondary to craniocerebral trauma. According to the clinical manifestations of patients and the reasons for the different choice of surgery.