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缺血性中风是发病和死亡的一个主要原因:英格兰和威尔士每年因脑血管病死亡达73500人。短暂性脑缺血发作(TIA)是预告即将中风的最重要症状,TIA发生后最初几个月危险性最大。这就需要在TIA患者中有预示血管病变进展的指数,以便能集中地治疗那些最危险的病变。脑血管病变者中血小板α-颗粒释放的一个标记β-血栓球蛋白(BTG)和纤维蛋白酶形成的纤维蛋白的一个标记纤维蛋白肽A(FPA)的血浆浓度可增高。作者旨
Ischemic stroke is one of the major causes of morbidity and mortality: 73,500 deaths from cerebrovascular diseases occur each year in England and Wales. Transient ischemic attack (TIA) is the foremost symptom of an imminent stroke, with the greatest risk in the first few months after TIA. This requires an index predicting the progression of vascular disease in TIA patients so that the most dangerous lesions can be treated intensively. Plasma concentrations of one labeled fibrinopeptide A (FPA), a marker of beta-thrombin (BTG) and fibrin-forming fibrin released by platelet alpha-particles in cerebrovascular disease, may be increased. Author purpose