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目的观察甲硝唑氢氧化钙碘仿糊剂应用于难治性慢性根尖周炎根管内封药消毒的临床效果。方法选择经过根管预备清理后封药消毒3次以上症状未消失的80例难治性慢性根尖周炎病例,随机分为实验组与对照组,实验组(40例)在根管内封入甲硝唑氢氧化钙碘仿糊剂进行消毒,对照组(40例)在根管内继续封入FC棉捻消毒,对两组根管封药消毒效果进行临床观察和比较。结果实验组封药有效率为92.5%(37/40),对照组封药有效率为47.5%(19/40),两组的封药后的有效率存在极显著差异(χ2=19.28,P<0.01)。结论对于甲醛甲酚根管内反复换药疗效不佳的难治性慢性根尖周炎病例,在根管内封入甲硝唑氢氧化钙碘仿糊剂进行消毒疗效显著。因此甲硝唑氢氧化钙碘仿糊剂可作为难治性慢性根尖周炎的有效治疗方法。
Objective To observe the clinical efficacy of metronidazole calcium hydroxide iodoform paste in root canal disinfection of refractory chronic apical periodontitis. Methods Eighty cases of refractory chronic periapical periodontitis, which had not disappeared after three weeks of sewer disinfection, were randomly divided into experimental group and control group. The experimental group (40 cases) was enclosed in the root canal Metronidazole calcium hydroxide iodoform paste disinfection, the control group (40 cases) continue to seal FC cotton twist disinfection in the root canal, the two groups of root canal sealing drug disinfection effect of clinical observation and comparison. Results The effective rate of the sealant was 92.5% (37/40) in the experimental group and 47.5% (19/40) in the control group. There was a significant difference in the effective rate between the two groups (χ2 = 19.28, P <0.01). Conclusion For refractory chronic periapical periodontitis with poor curative effect in repeated replacement of formaldehyde cresyled root canal, metronidazole calcium hydroxide iodoform paste was sealed in the root canal for disinfection. Metronidazole calcium hydroxide iodoform paste can be used as an effective treatment of refractory chronic apical periodontitis.