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目的检测脑梗死患者血清超敏C反应蛋白(hs-CRP)的水平,探讨hs-CRP与脑梗死发生的关系。方法收集2011年7～8月脑梗死患者108例,其中动脉硬化性血栓形成性脑梗死(ABI)43例、脑栓塞(CE)27例、腔隙性脑梗死(LI)38例;收集体检健康者50例作为正常对照组。采用OLYMPUS AU5400测定所有研究对象的血清hs-CRP水平。结果 ABI组、CE组、LI组的血清hs-CRP水平均明显高于正常对照组(P<0.01)。此外,CE组的血清hs-CRP水平略高于ABI组,ABI组的血清hs-CRP水平略高于LI组,但三组间的差异不明显(P>0.05)。结论脑梗死患者血清hs-CRP水平明显升高,hs-CRP可作为脑梗死发生的一个预测因素。
Objective To detect the level of serum hs-CRP in patients with cerebral infarction and to explore the relationship between hs-CRP and the occurrence of cerebral infarction. Methods A total of 108 patients with cerebral infarction from July to August in 2011 were collected, including 43 cases of arteriosclerotic thrombotic cerebral infarction (ABI), 27 cases of cerebral embolism (CE) and 38 cases of lacunar infarction (LI) 50 healthy people as a normal control group. All subjects were tested for serum hs-CRP levels using the OLYMPUS AU5400. Results The levels of serum hs-CRP in ABI, CE and LI groups were significantly higher than those in normal control group (P <0.01). In addition, the serum hs-CRP level in CE group was slightly higher than that in ABI group. The serum hs-CRP level in ABI group was slightly higher than that in LI group, but there was no significant difference among the three groups (P> 0.05). Conclusions Serum hs-CRP levels in patients with cerebral infarction were significantly increased, hs-CRP can be used as a predictor of cerebral infarction.