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心肌梗死患者用溶栓治疗可改善预后,但颅内出血(ICH)的危险性增加,某些病例行溶栓治疗的危险性可能大于收益性。本文从5个来源收集资料对溶血治疗期间发生ICH的危险因素进行评定。资料的5个来源为:荷兰溶栓疗法登记处与欧洲协作研究组;GISSI—Ⅰ与国际研究组;TIMI—Ⅰ(心肌梗死溶栓治疗Ⅰ期研究);TAMI(心肌梗死溶栓与血管成形术研究);ISAM(急性心肌梗死静注链激酶研究)。上述资料共提供ICH病例150例及与
Thrombolytic therapy in patients with myocardial infarction can improve the prognosis, but the increased risk of intracranial hemorrhage (ICH), in some cases the risk of thrombolytic therapy may be greater than the profitability. This article collects information from five sources on the risk factors for the development of ICH during hemolysis. Five sources of data were: Dutch Thrombolytic Registry and European Collaborative Research Group; GISSI-I and International Study Group; TIMI-I (Phase I Study of Thrombolytic Therapy for Myocardial Infarction); TAMI (Thrombolysis and Angioplasty in Myocardial Infarction Surgery research); ISAM (acute myocardial infarction intravenous streptokinase research). The above information provided a total of 150 cases of ICH and