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目的:分析乳腺黏液型脂肪肉瘤合并浸润性导管癌及纤维腺瘤的临床及病理特点。方法:报告1例同侧乳腺黏液型脂肪肉瘤合并浸润性导管癌及纤维腺瘤并结合文献进行复习。结果:该患者发现左乳3个互不相连的肿物。镜下3个肿物分别诊断为黏液型脂肪肉瘤、浸润性导管癌及纤维腺瘤。免疫组化显示黏液型脂肪肉瘤与浸润性导管癌分别为表达上皮源性及间叶源性标志物。治疗方式为早期根治性手术切除,术后辅助化疗。该例术后随访12个月未见复发或转移。结论:乳腺黏液型脂肪肉瘤少见,同时伴发浸润导管癌以及纤维腺瘤尤为罕见。治疗方式应首选根治性手术切除及术后辅助化疗。
Objective: To analyze the clinical and pathological characteristics of breast mucinous liposarcoma with invasive ductal carcinoma and fibroadenoma. Methods: One ipsilateral mammary mucin liposarcoma was reported with invasive ductal carcinoma and fibroadenoma and reviewed with literature. Results: The patient found 3 unrelated masses of left breast. Three microscopic tumors were diagnosed as mucinous liposarcoma, invasive ductal carcinoma and fibroadenoma. Immunohistochemistry showed that mucin-type liposarcoma and invasive ductal carcinoma were epithelial-derived and mesenchymal-derived markers, respectively. Treatment for radical radical resection, postoperative adjuvant chemotherapy. The cases were followed up for 12 months without recurrence or metastasis. Conclusions: Mucous liposarcoma in breast is uncommon, accompanied by infiltrating ductal carcinoma and fibroadenoma. The treatment should be the first choice of radical surgical resection and postoperative adjuvant chemotherapy.