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应用免疫荧光标记流式细胞仪分析技术,对48例发作期、30例缓解期哮喘患儿和30例正常儿童的淋巴细胞IgE低亲和力受体(CD23)阳性率进行检测,同时检测血清中sCD23和IgE含量。结果显示:哮喘发作期和缓解期淋巴细胞CD23阳性率、血清sCD23和IgE含量均显著高于正常儿童;发作期患儿CD23阳性率与血清IgE含量呈显著正相关,与血清sCD23含量无相关性;血清sCD23与IgE含量之间在各组内均无相关性。提示CD23和sCD23与哮喘的发病有关。
The positive rates of CD23 in lymphocytes were detected in 48 attacking patients, 30 remission asthmatic children and 30 normal children by immunofluorescence labeling flow cytometry. Meanwhile, the serum sCD23 And IgE content. The results showed that the positive rate of CD23 and the level of sCD23 and IgE in lymphocytes were significantly higher than those in normal children during the onset and remission of asthma. The positive rate of CD23 in serum was positively correlated with the level of serum IgE in seizure and had no correlation with serum sCD23 There was no correlation between serum sCD23 and IgE levels in each group. Tip CD23 and sCD23 and the incidence of asthma.