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目的:本文介绍应用液氮保存的、取材于新生儿带瓣大动脉,作为婴幼儿复杂先天性心脏病矫治术中应用的经验。方法:1993年10月至1994年12月间27例患儿在体外循环下行重症法乐四联症或右室双出口根治术。15例应用我院制备、具有活性的同种带瓣大动脉跨环加宽右室流出道。平均体重为9.50±2.04kg,另12例则用自体心包片为跨环加宽右室流出道材料,平均体重10.42±1.95kg。术后1周至9个月间用超声心动图评价肺动脉反流程度。结果:全组无死亡,术后9个月同种瓣组肺动脉瓣反流40.12±2.56%,自体心包组肺动脉瓣反流70.00±10.61%。结论:液氮保存的新生儿带瓣大动脉具有良好活性,作为跨肺动脉瓣环补片材料矫治复杂先天性心脏病时肺动脉反流明显低于自体心包片。
Objective: This article describes the application of liquid nitrogen preservation, drawn from the newborn aortic valve, as an infantile complex congenital heart disease correction surgery application experience. Methods: From October 1993 to December 1994, 27 children underwent cardiopulmonary bypass with severe tetralogy of Fallot or radical double outlet radical hysterectomy. 15 cases were prepared in our hospital, with the activity of the same type of aortic valve widening across the right ventricular outflow tract. The average body weight was 9.50 ± 2.04kg, and the other 12 cases were used to widen the right ventricular outflow tract material with an average diameter of 10.42 ± 1.95kg. Echocardiography was used to evaluate the degree of pulmonary regurgitation between 1 week and 9 months after surgery. Results: There was no death in the whole group. The pulmonary valve regurgitation was 40.12 ± 2.56% in the same type of valve group and 70.00 ± 10.61% in the autologous pericardial group at 9 months after operation. Conclusions: Neonatal aortic valve preserved in liquid nitrogen has a good activity. Pulmonary artery regurgitation was significantly lower than autologous pericardium in the treatment of complicated congenital heart disease as a trans-pulmonary valve material.