据世界卫生组织估计,全世界约有2.5亿人患有重度以上听力损失,其中2/3在发展中国家,我国是最大的发展中国家,听力障碍残疾人有2057万,其中900多万是老年人,可以说老年性听力损失患者是我国最大的听力障碍群体〔1〕。笔者就近年来利用老鼠模型研究老年性听力损失的组织病理和分 WHO estimates that about 250 million people worldwide suffer from severe or severe hearing loss, two thirds of them in developing countries and the largest developing country in the world, with 20.57 million people with hearing disabilities, of whom more than 9 million are Elderly people, can be said that senile patients with hearing loss is China’s largest hearing-impaired population 〔1〕. In recent years, I use the mouse model to study the age-related hearing loss histopathology and points