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组织型纤溶酶原激活剂(tissue-typePlasmlnogenactlvator,t-PA)与血栓中的纤维蛋白结合,激活纤溶酶原转化成纤溶酶,水解血栓中的纤维蛋白使血栓溶解。但在正常人体内t-PA受纤溶酶原激活剂抑制物(Plasmino-g””“ctivatorinh比norPAI)的快速抑制。作者对不同病程脑
Tissue-type Plasminogen activator (t-PA) binds to fibrin in the thrombus and activates plasminogen to convert it into plasmin, hydrolyzing the fibrin in the thrombus to thrombolytic. However, in normal humans, t-PA is rapidly inhibited by plasminogen activator inhibitor Plasmino-g (“ctivatorinh”) compared to norPAI