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目的探讨脉搏波传导速度(PWV)与脑血管病的相关性及其在脑血管病防治中的意义。方法测定89例急性脑血管病患者的颈动脉-股动脉脉搏波传导速度(cf-PWV),30例非脑血管病查体者为对照,比较分析各组的cf-PWV及脑血管病不同发病形式、发病部位患者的cf-PWV,分析吸烟及饮酒对脑血管病患者血管改变的影响。结果①脑梗死组和脑出血组的双侧cf-PWV均明显高于对照组(P<0.01,P<0.05);②皮质皮质下梗死组双侧cf-PWV均明显高于小脑脑干组(P<0.01),皮质下梗死组分别与小脑脑干组及皮质皮质下梗死组的cf-PWV差异不显著(P>0.05);③脑出血组按出血部位不同分组的cf-PWV差异不显著(P>0.05);④脑血管病患者中,吸烟组双侧cf-PWV均明显低于不吸烟组(P<0.05);不饮酒组、轻度饮酒组和大量饮酒组的cf-PWV差异不明显(P>0.05)。结论①PWV是与脑梗死、脑出血的发生密切相关的重要因素;②吸烟可能使发生脑血管病的PWV阈值下降,从而增加脑血管病的发生风险。
Objective To investigate the relationship between pulse wave velocity (PWV) and cerebrovascular disease and its significance in the prevention and treatment of cerebrovascular disease. Methods The carotid-femoral arterial pulse wave velocity (cf-PWV) was measured in 89 patients with acute cerebrovascular disease and 30 non-cerebrovascular disease patients were compared. The levels of cf-PWV and cerebrovascular disease in each group were compared Incidence and incidence of patients with cf-PWV, analysis of smoking and drinking on vascular disease in patients with vascular changes. Results ① Both cf-PWV in cerebral infarction group and cerebral hemorrhage group were significantly higher than those in control group (P <0.01, P <0.05); ② The both sides of cortical subcortical infarction group cf-PWV were significantly higher than those in cerebellum (P <0.01). There was no significant difference in cf-PWV between the subcortical infarction group and the cerebellum brainstem group and the cortical subcortical infarction group (P> 0.05) .③The differences of cf-PWV in the cerebral hemorrhage group (P> 0.05) .④The levels of cf-PWV in smoking group were significantly lower than those in non-smoking group in patients with cerebrovascular disease (P <0.05); cf-PWV in non-drinking group, mild drinking group and heavy drinking group The difference was not significant (P> 0.05). Conclusions ①PWV is an important factor closely related to the occurrence of cerebral infarction and cerebral hemorrhage. ② Smoking may decrease the PWV threshold of cerebrovascular disease and increase the risk of cerebrovascular disease.