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目的 评价氟康唑静脉滴注后改口服的序贯疗法治疗老年人肺部白色念珠菌感染的疗效及不良反应。方法 用氟康唑序贯疗法治疗老年人肺部白色念珠菌感染 60例 ,第 1d 40 0mg静脉滴注 ,第 2d改为 2 0 0mg静脉滴注 ,每日 1次 ,连续用 7～ 10d后改口服 ,2 0 0mg/d ,每天 1次。疗程 3～ 4周。 结果 总有效率为 90 0 % ,白色念珠菌清除率为 85 0 % ,不良反应发生率为 8 3 %。结论 氟康唑序贯疗法疗效高 ,不良反应少 ,用药方便 ,尤适用于老年人
Objective To evaluate the efficacy and side effects of oral sequential oral instillation of fluconazole in the treatment of pulmonary Candida albicans infection in the elderly. Methods Sixty cases of pulmonary Candida albicans infection were treated with fluconazole sequential therapy. The first day was 40 mg intravenously and the second day was changed to 200 mg intravenously once daily for 7-10 days Change oral, 200mg / d, 1 times a day. Course of 3 to 4 weeks. Results The total effective rate was 90 0%, Candida albicans clearance rate was 85 0%, adverse reaction rate was 83%. Conclusions Fluconazole sequential therapy has the advantages of high curative effect, less adverse reactions, convenient medication, especially for the elderly