论文部分内容阅读
目的探讨子宫内膜癌的发病趋势和临床病理特点。方法回顾性分析天津市滨海新区塘沽妇幼保健院和天津医科大学总医院1984年至2010年收治的961例子宫内膜癌患者的临床病理资料,并分为1984-1992年、1993-2001年、2002-2010年3个时段进行对比分析。结果 1子宫内膜癌呈逐年上升趋势,3个时段发病例数也逐年增多,≤45岁患者例数逐年增多,但3个时段所占比例呈下降趋势(P>0.05)。2发病年龄24~89岁,平均(55.8±12.8)岁,高发年龄51~60岁,占37.98%。3病理组织类型以子宫内膜样腺癌为主,占86.58%,非子宫内膜样癌逐年显著增加,占13.42%,其组织学分级、肌层浸润的深度及手术病理分期Ⅲ、Ⅳ期的比例均高于子宫内膜样腺癌,以浆液性乳头状腺癌多见,占52.71%。结论子宫内膜癌呈上升趋势,≤45岁患者例数逐年增多;非子宫内膜样癌有所增加,其分化低、侵袭性强、预后差,应高度重视。
Objective To investigate the incidence of endometrial cancer and clinicopathological features. Methods The clinical and pathological data of 961 patients with endometrial cancer who were treated in Tanggu Maternal and Child Health Hospital of Tianjin Binhai New Area and Tianjin Medical University General Hospital from 1984 to 2010 were retrospectively analyzed and divided into 1984-1992, 2002-2010 three periods for comparative analysis. Results 1 Endometrial cancer showed an upward trend year by year, and the number of cases in three periods increased year by year. The number of patients aged ≤45 years increased year by year, but the proportion of three periods showed a decreasing trend (P> 0.05). 2 age of onset of 24 to 89 years old, with an average (55.8 ± 12.8) years old, high incidence of 51 to 60 years old, accounting for 37.98%. The pathological type was mainly endometrioid adenocarcinoma, accounting for 86.58%. The non-endometrioid carcinoma was significantly increased year by year, accounting for 13.42%. The histological grade, the depth of myometrial invasion and the stage of surgical pathology Ⅲ, Ⅳ Were higher than endometrial adenocarcinoma, serous papillary adenocarcinoma more common, accounting for 52.71%. Conclusion The incidence of endometrial cancer is on the rise. The number of patients aged ≤45 years is increasing year by year. The non-endometrioid carcinoma is increased, which is characterized by low differentiation, strong invasion and poor prognosis.