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本文应用Ｇｒｉｅｓｓ法及放射免疫法测定６０例妊娠高血压综合征患者、２３例正常晚期妊娠妇女、２２例健康非孕妇女血浆ＮＯ－２／ＮＯ－３和ＥＴ－１水平。结果表明：妊高征患者血浆ＮＯ－２／ＮＯ－３下降，ＥＴ－１上升。两者呈明显负相关。本文结果提示：一氧化氮与妊高征病情呈负相关；ＥＴ－１与妊高征病情呈正相关；ＮＯ和ＥＴ－１在妊高征中呈负相关。ＮＯ／ＥＴ－１比值越小，妊高征病情越重。
In this paper, the plasma levels of NO-2 / NO-3 and ET-1 in 60 patients with pregnancy induced hypertension, 23 normal pregnant women and 22 healthy non-pregnant women were measured by Griess method and radioimmunoassay. The results showed that plasma NO-2 / NO-3 level decreased and ET-1 level increased in patients with PIH. The two were significantly negative correlation. Our results suggest that nitric oxide is negatively correlated with PIH, ET-1 is positively correlated with PIH, NO and ET-1 are negatively correlated with PIH. The smaller the ratio of NO / ET-1, the more severe PIH.