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非惊厥性癫持续状态(NCSE)指大脑持续性放电活动>30 min,同时伴某些精神、意识或行为异常,但缺乏惊厥性症状的临床病理情况。NCSE的分类较复杂,传统分为全面性与局限性,如失神癫发作和复杂局限发作持续状态,目前公认以起病年龄为特征的临床分类。临床表现为轻微或不显性运动、情感、唤醒、认知、记忆、视觉或意识障碍。典型脑电图包括节律性、全脑同步性3.0～3.5 Hz棘-慢复合波;不典型者为节律或非节律性<3.0 Hz棘-慢复合波、多棘-慢复合波,节律性δ慢波兼有棘波或小尖波持续发放。边缘性脑电图可能代表一种发作与发作后、发作期与发作间期,甚至性与非性之间的代谢或器质性脑功能动态异常状态,又称为周期性放电脑电图,包括周期性单侧性放电(PLEDs),双侧独立同步周期性单侧性放电(BIPLEDs),伴一过性节律性放电的周期性单侧性放电,广泛性周期性性放电和三相波,刺激诱导节律周期性或发作性放电等。NCSE的临床诊断较困难,主要根据不典型神经症状与异常行为,进行性神经心理功能异常,持续或反复阵发性性放电,缺乏明显的运动性发作表现;其次,依据静脉或口服抗癫药物治疗能够改善症状或缓解病情。脑电图包括频繁或持续广泛性或局灶性棘波或棘-慢波放电,伴波幅、频率和分布的异常变化;全面惊厥性发作或癫持续状态后昏迷伴PLEDs或BIPLEDs。
Non-convulsive status epilepticus (NCSE) refers to persistent brain discharge activity> 30 min, accompanied by some mental, mental or behavioral abnormalities, but lack of clinical and pathological conditions of convulsive symptoms. NCSE classification is more complex, the traditional is divided into comprehensive and limitations, such as absence of epilepsy seizures and complicated confined episodes sustained status, is currently recognized as the clinical features of onset age. Clinical manifestations are mild or insignificant motor, emotional, arousal, cognitive, memory, visual or unconsciousness. Typical EEG patterns include rhythmic, brain-synchronous 3.0-3.5 Hz spine-slow complexes; atypical rhythmic or non-rhythmic <3.0 Hz spine-slow complexes, spines-slow complexes, rhythmic δ Slow wave both spike or small spike continued release. Marginal EEG may represent a seizure and after the attack, attack and seizure interval, or even between the malaria and non-malaria metabolic or organic abnormalities of brain function, also known as cyclical discharge EEG The graphs include periodic unilateral PD discharges (PLEDs), bilateral independent synchronized periodic unilateral discharges (BIPLEDs), periodic unilateral discharges with transient rhythmic discharges, Sexual discharge and three-phase wave, stimulate the rhythm induced periodic or episodic discharges. Clinical diagnosis of NCSE is more difficult, mainly based on atypical neurological symptoms and abnormal behavior, progressive neuropsychological abnormalities, persistent or recurrent paroxysmal nocturnal discharge, the lack of significant motor seizures; Second, based on intravenous or oral anti-epilepsy Medication can improve symptoms or relieve illness. EEG includes frequent or persistent extensive or focal spikes or spikes - slow wave discharge, with abnormal amplitude, frequency and distribution of abnormal changes; full convulsive seizures or epileptic persistence after coma with PLEDs or BIPLEDs.