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20年来，辣椒素在初级传入伤害性感受器的神经生物学研究及慢性痛的新的治疗举措方面具有十分重要的地位。其主要原因是由于它具有显著的细胞特异性、它的作用方式几乎均可归结为一种机制──激活初级传入感觉神经元的C纤维[80％都是多觉伤害性感受器（polymodelnociceptor）]?
For 20 years, capsaicin plays a very important role in the neurobiology of primary afferent nociceptors and new therapeutic measures for chronic pain. The main reason for this is that due to its remarkable cellular specificity, almost all of its actions can be attributed to a mechanism that activates C-fibers in primary afferent sensory neurons [80% are polymodel nociceptors ]?