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近年的研究表明，肺动脉胶原堆积增多与肺动脉高压的形成有关，MialadejO报道血管紧张素转化酶（ACE）抑制剂可抑制自发性高血压大鼠主动脉胶原增生并防止高血压的发生。本实验旨在观察ACE抑制剂酉拉普利对缺氧大鼠肺动脉压力，肺动脉胶原堆积及肺动脉ACE活性的影响。材料与方
In recent years, studies have shown that increased pulmonary artery collagen accumulation and pulmonary hypertension, MialadejO reported that angiotensin-converting enzyme (ACE) inhibitors can inhibit spontaneous hypertensive rat aortic collagen proliferation and prevent the occurrence of hypertension. The aim of this study was to investigate the effect of the ACE inhibitor-chelazuril on pulmonary artery pressure, pulmonary artery collagen accumulation and pulmonary artery ACE activity in hypoxic rats. Material and side