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由Vale等人分离出具有促皮质激素活性41氨基酸多肽后,大量免疫细胞化学研究阐明大脑和脊髓含有核周体和纤维的促皮质激素释放因子(CRF)的分布,CRF-免疫反应性(ir)神经原的致
After isolation of a 41 amino acid polypeptide with corticotropin activity by Vale et al., A large number of immunocytochemical studies have elucidated the distribution of corticotropin-releasing factor (CRF) in the brain and spinal cord with perinuclear and fibrous forms, CRF-immunoreactivity ) Neurogen induced