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目的对人参茎叶总皂苷片、运动疗法、人参茎叶总皂苷片联合运动疗法对强直性脊柱炎(AS)患者关节疼痛功能障碍的改善程度进行观察。方法 90例AS患者随机分为人参茎叶总皂苷片组、运动疗法组、人参茎叶总皂苷片联合运动疗法组各30例。人参茎叶总皂苷片组使用人参茎叶总皂苷片治疗、运动疗法组仅进行运动疗法治疗、人参茎叶总皂苷片联合运动疗法组采用人参茎叶总皂苷片联合运动疗法治疗。治疗90d后对各组患者的疗效及关节疼痛功能障碍指标进行评价。结果人参茎叶总皂苷片联合运动疗法组的总疗效为96.7%,人参茎叶总皂苷片组的总疗效为93.3%,运动疗法组的总疗效为80.0%。人参茎叶总皂苷片联合运动疗法组、人参茎叶总皂苷片组与运动疗法组总疗效比较呈显著性差异(P<0.05)。参茎叶总皂苷片联合运动疗法组、人参茎叶总皂苷片组与运动疗法组治疗前后关节疼痛功能障碍各项观察指标比较呈显著性差异(P<0.05)。结论人参茎叶总皂苷片联合运动疗法、人参茎叶总皂苷片与运动疗法的疗效显著性差异,未见不良反应。人参茎叶总皂苷片联合运动疗法效果更好,值得临床推广应用。
Objective To observe the improvement of joint pain dysfunction in patients with ankylosing spondylitis (AS) by combining total saponin tablets of ginseng stem and leaf, exercise therapy and total ginsenoside tablets of ginseng stem and leaf. Methods Ninety AS patients were randomly divided into three groups: total ginsenoside group, exercise group, total ginsenoside group and exercise group. Ginseng stem and leaf total saponin tablets using ginseng stem and leaf total saponin tablets, exercise therapy group only for exercise therapy, ginseng stem and leaf total saponin combined with exercise therapy group ginseng stem and leaf total saponin tablets combined with exercise therapy. After 90 days of treatment, the curative effect of each group of patients and the index of joint pain dysfunction were evaluated. Results Total ginseng stem and leaf total saponin combined with exercise therapy group was 96.7%, total ginseng stem and leaf total saponin group was 93.3%, and exercise group was 80.0%. The total curative effect of ginseng stem and leaf total saponin combined exercise therapy group, ginseng stem and leaf total saponin tablet group and exercise therapy group showed significant difference (P <0.05). There were significant differences (P <0.05) among the indexes of joint pain and dysfunction before and after the treatment of total saponin tablets and exercise group, total saponin tablets group of ginseng stem and leaves and exercise therapy group. Conclusion ginseng stem and leaf total saponin combined exercise therapy, ginseng stem and leaf total saponin tablets and exercise therapy significant difference, no adverse reactions. Ginseng stem and leaf total saponin combined exercise therapy is better, it is worthy of clinical promotion and application.