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目的分析中国2009年308个县(区、市,下同)流行性乙型脑炎(乙脑)减毒活疫苗(Japanese Encephalitis Attenuated Live Vaccine,JEV-L)群体性预防接种效果,为制定乙脑预防控制策略提供参考。方法比较不同地区接种对象群体性预防接种前后,乙脑的发病专率、构成比、预防分值。结果 2010年308县<10岁儿童乙脑发病率低于2007～2009年;群体性预防接种后,308个县接种对象的乙脑发病专率由7.53/10万下降至4.35/10万,预防分值为42.35%,接种对象乙脑病例数构成比由68.33%下降至54.00%;各省预防分值与JEV-L接种率无明显相关性(rs=0.28,P=0.38)。结论 JEV-L群体性预防接种降低了乙脑发病水平,达到了预期效果。
Objective To analyze the population vaccination effects of Japanese Encephalitis Attenuated Live Vaccine (JEV-L) in 308 counties (autonomous regions and municipalities in China) in 2009, Brain prevention and control strategies for reference. Methods The incidence rate, constitutional ratio and prevention score of Japanese encephalitis B before and after vaccination were compared among groups vaccinated in different areas. Results In 2010, the incidence of Japanese encephalitis in children <10 years old was lower than that in 2007-2009. The incidence of Japanese encephalitis inoculated in 308 counties dropped from 7.53 / 100000 to 4.35 / 100000 after population vaccination, The score was 42.35%. The proportion of cases with JE vaccination decreased from 68.33% to 54.00%. There was no significant correlation between the prevention score and the vaccination rate of JEV-L (rs = 0.28, P = 0.38). Conclusions JEV-L group vaccination can reduce the incidence of Japanese encephalitis and achieve the expected results.