1975年以来,为深入探讨EHF 发病学和病因学,我们首次利用光学高分辨半薄切片技术和电子显微镜对EHF 各期死亡病例进行了观察,揭示了超微病变特点和变化规律。其中许多超微病变从未报告过,对于了解EHF 本质具有重要意义。本文着重描述基本超微病理特点,有关内涵物等一些特殊变化将另文讨论。 Since 1975, for the first time to investigate the pathogenesis and etiology of EHF, we first observed the death of EHF patients by using optical high-resolution semi-thin section technique and electron microscope, and revealed the characteristics and changes of ultra-lesion. Many of these superficial lesions have never been reported and are important for understanding the nature of EHF. This article focuses on describing the basic ultrastructural features, some of the specific changes such as the content will be discussed in another paper.